Orgestra
Organoid technologies for disease modelling, drug discovery and development for rare diseases.
About the Orgestra project
We are an EU funded MSCA Joint Doctoral network that will train thirteen doctoral candidates in developing personalized disease models using stem cell-derived organoids for rare diseases, including the lung and kidney diseases, cystic fibrosis and cystinosis.
Research will aim to identify pathogenetic mechanisms, druggable targets, and drug mode of action for effective and innovative treatment strategies and to classify the pathway to clinic. We will also address ethical and regulatory issues to foster acceptance and implementation of organoid models and develop a living technologies toolset to enable a swift transfer from bench to bedside.
ORGESTRA is a four-year project funded by the EC HORIZON–MSCA-2023-DN-JD Grant Agreement No 101120108, coordinated by the University of Utrecht. The project starts 1st January 2024 and will end in December 2027.
The network is made up of fourteen partners from seven European countries providing international, intersectoral and interdisciplinary training that brings together molecular biologists, engineers, pharmacologists, clinicians, epidemiologists and ethicists, to give each of our doctoral candidates a unique, joint-doctoral training experience complemented by a rich network training programme.
Meet our Doctoral Candidates
Our network partners are
Associate Partners undertaking training/secondments or degree awarding include:
Latest news
ORGESTRA attends the European Cystic Fibrosis Conference 2025
What have our PhD students been up to?The 48th Europe Cystic Fibrosis Conference was held for 3 - 7 June 2025, in Milan, Italy. From the ORGESTRA community, two PhD students, Jorge Madrid Paredes (DC13) and Woosub Shin (DC12), and two PIs, Kors van der Ent and...
May is Cystic Fibrosis Awareness Month
This month ORGESTRA supports Cystic Fibrosis Awareness by highlighting the umet need and the advances in personalised medicine that the project aims to contribute to.[dipl_image_card_carousel _builder_version="4.27.4" _module_preset="default"...