One of our DCs, Ananya Singh, was recently invited for a short interview by a KU Leuven Master’s student Sabrina Fiore as part of her Master’s thesis research, “Navigating Dual Worlds: Identity Formation and Integration Process among Indians in Leuven between Flemish Context and Indian Heritage.” The interview focused on the experiences of first-generation Indian migrants in Leuven, particularly within academic and professional environments.

During the conversation, Ananya shared her personal journey of adapting to life in Leuven while maintaining a strong connection to her Indian heritage. They discussed topics such as cultural adjustment, identity, challenges faced in professional spaces, and the balance between integration into the Flemish context and preserving cultural roots. It was a meaningful exchange that highlighted the diverse experiences of the Indian community in Europe and reflected the broader journey of many non-European MSCA fellows building their careers while navigating life in an international environment.

From 2–6 February 2026, ORGESTRA fellows, partners and associate partners gathered at the Faculty of Sciences, University of Lisbon for School 2: Filling the Drug Development Pipeline.

The programme combined molecular disease mechanisms, high-throughput screening, RNA therapies, drug delivery, and viral vector design, alongside wet lab and computational training.

The scientific programme featured contributions from Margarida Amaral, Luka Clarke, André Maia, Hugo Botelho, Gimano Amatngalim, Roos Masereeuw, Catherine Bell, Filipa Ferreira, Mykaella Mestre, António Pombinho, Rik Gijsbers, Jenny van Asbeck-van der Wijst, Alessandra Bragonzi, and Tracey MacCauley. Sessions spanned cystic fibrosis molecular mechanisms and premature termination codon biology, high-content screening and statistical analysis of image-based drug discovery data, drug safety and delivery strategies, RNA therapeutics, viral vector design, and patient–researcher partnerships in rare diseases.

A central component of the school was hands-on high-throughput screening training. Fellows participated in wet lab sessions focused on sample handling and automated image acquisition, followed by IT labs using CellProfiler for segmentation and quantitative analysis of image-based drug screening data, led by Hugo Botelho.

The school also hosted work package meetings and the ORGESTRA Mid-Term Review, providing fellows the opportunity to present their research progress and receive structured feedback from partners and the REA Project Officer.

The week concluded with presentation awards recognising scientific communication and creativity:

🏆 Best Poster Award – Mark Leahy
🎥 Best Video Award – Aurora Licaj

ORGESTRA School 2 strengthened technical expertise, reinforced cross-institutional collaboration, and advanced our shared goal of accelerating therapies for rare diseases.

The project mid-term review meeting took place in Lisbon, Portugal on 6th February 2026, hosted by the Faculty of Scinces, University of Lisbon.

The meeting was well attended by network members and included presentations and posters from our DCs.

Congratulations to Lena Heer – DC10,  for winning a poster award at the Utrecht Institute for Pharmaceutical Sciences biannual meeting January 2026.

On Sunday, 23rd November, two of our DCs welcomed many curious minds to the Open Science Day at KU Leuven as part of the Leuven Institute for Rare Diseases. From poster presentations, deep-dive explanations and lab tours, both DCs brought their research on cystinosis closer to the public. Children and grandparents had the opportunity to get a behind-the-scenes look at cutting-edge research on rare diseases and novel gene-based therapies.

Ananya Singh (DC8) and Roger Mora (DC9) explain more:

“We believe that accessible research strengthens the link between our work and our social purpose. It was exciting to witness their enthusiasm and curiosity about our research. We hope this event inspired the next generation and strengthened the general public’s confidence in science. Thank you to everyone who joined the event, engaged in thoughtful conversations, and for making science come alive”.

On October 16–17, we were invited to iBET in Oeiras, Lisbon, for a two-day workshop on Research and Transferable Skills.

💡 Day 1 focused on the research at iBET, exploring advanced 3D cell models, omics technologies, and bioprocesses for stem cells and organoids, illustrated through case studies on bioreactor technology. This session was guided by Dr. Margarida Serra, head of Stem and Immune Cells Bioengineering Lab, and some members of her team. Participants even took on the challenge of building their own bioreactor model!

🚀 Day 2, guided by Dr. Ritchie Head (CERAT) and Dr. Jenny van der Wijst (MERCURNA), was dedicated to Innovation and Enterprise, exploring how to transform research into real-world impact and strengthen key entrepreneurial and transferable skills.

A big thank you to everyone involved in organizing these two great days, and to iBET for kindly hosting us and making the experience so enjoyable!

🏢 About iBET

iBET is a private, not-for-profit research organization dedicated to advancing Biotechnology and Health Sciences. It focuses on scientific research and technological development, bridging academia and industry through innovation and collaboration. With over 50 laboratories, GMP-certified analytical units, and access to cGMP manufacturing, the company supports both early and late-stage R&D across its Health & Pharma and Food & Health divisions. Its multidisciplinary team includes more than 110 PhDs, 75 research fellows, and 80 technicians, driving impactful research and innovation.

🔗 To learn more about their work, visit the website: https://www.ibet.pt/

Leica’s motto — “From Eye to Insight” — perfectly captured the spirit of our recent training and facility tour at the EMBL Imaging Centre in Heidelberg.

Over two immersive days, we explored how cutting-edge imaging technologies go far beyond visualization: they are true drivers of discovery and clinical insight.

We had the opportunity to experience an impressive range of Leica microscopes and learn about their diverse applications:

 ✨ Stellaris Confocal System – delivering high-resolution imaging of complex cellular structures.

💡 Thunder SD – showing how computational clearing can bring clarity back to thick biological samples.

🧬 Viventis Deep – extending the boundaries of 3D tissue imaging.

🧫 Mica – an all-in-one, intuitive microscope that simplifies workflows.

✂ Laser Microdissection (LMD) – enabling precise recovery of single cells for downstream analysis.

🌈 Stellaris DIVE Multiphoton – revealing the power of next-generation deep-tissue and live-sample imaging.

A huge thank you to the Leica Microsystems team for their expertise, enthusiasm, and support throughout the sessions. Truly a great example of science and technology coming together to empower researchers!

For more information on this event go to: https://weekendvandewetenschap.nl/activiteiten/2025/mini-niertjes-kweken/